EndovaScular Versus mediCaL mAnagement of Uncomplicated Type B Intramural heMatoma Trial (ESCLAIM)
Status:
Recruiting
Trial end date:
2024-03-01
Target enrollment:
Participant gender:
Summary
This trial is a multicenter, open-label and prospective randomized controlled study to
compare 1-year outcomes of uncomplicated type B intramural hematoma (IMH) patients undergoing
thoracic endovascular aortic repair (TEVAR) plus optimal medical therapy (OMT) with that of
those undergoing OMT alone. The primary objective is to test the hypothesis that 1-year
aortic-related adverse events are lower in TEVAR plus OMT group than that in OMT alone group.
The secondary objective is to test the hypothesis that 1-year all-cause mortality,
aortic-related mortality and re-intervention are lower in TEVAR plus OMT group than that in
OMT alone group.
Phase:
N/A
Details
Lead Sponsor:
Guangdong Provincial People's Hospital
Collaborators:
First Affiliated Hospital of Xinjiang Medical University Henan Provincial Chest Hospital Jiangmen Central Hospital Jieyang People's Hospital Shenzhen People's Hospital The First Affiliated Hospital of Guangzhou Medical University Wuhan Hanyang Hospital Xinqiao Hospital of Chongqing