Entinostat and Anastrozole in Treating Postmenopausal Women With TNBC That Can Be Removed by Surgery
Status:
Terminated
Trial end date:
2017-05-01
Target enrollment:
Participant gender:
Summary
This phase II trial is studying how well giving entinostat and anastrozole together works in
treating postmenopausal women with triple-negative breast cancer that can be removed by
surgery. Entinostat may stop the growth of tumor cells by blocking some of the enzymes needed
for cell growth. Estrogen can cause the growth of breast cancer cells. Hormone therapy using
anastrozole may fight breast cancer by blocking the use of estrogen by the tumor cells.
Giving entinostat together with anastrozole may be an effective treatment for breast cancer.
Phase:
Phase 2
Details
Lead Sponsor:
University of Maryland University of Maryland, College Park