Epidural Calcitonin in Lower Limb Amputation

• Status: Completed
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

A prospective randomized double-blind clinical trial design will be used in a cohort of sixty patients of both genders, physical status American Society of Anaesthesiologist (ASA) I and II who will undergo lower limb amputation, will be enrolled into the present study. Patients will divided randomly into two equal groups: Epidural Bupivacain-Calcitonin and fentanyl (BC) Group and Bupivacain- fentanyl (BF) Group, comprising of 30 patients each.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University
• Treatments: Bupivacaine; Calcitonin; Calcitonin Gene-Related Peptide; Epinephrine; Epinephryl borate; Fentanyl; Katacalcin; Lidocaine; Pharmaceutical Solutions; Racepinephrine; Salmon calcitonin

Criteria

Inclusion Criteria:

• prospective randomized double-blind clinical trial design will be used in a cohort of sixty patients of both genders

• physical status American Society of Anaesthesiologist (ASA) I and II

• will undergo lower limb amputation

Exclusion Criteria:

• history of pituitary gland dysfunction

• cardiac disease

• chronic obstructive respiratory disease

• contraindications to performing an epidural block such as:

• coagulation abnormalities

• spinal deformities, and

• patients allergic to local anesthetics and or calcitonin will be excluded from the study