Epidural Study of Patients With Chronic Lower Back Pain

• Status: Completed
• Trial end date: 2011-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine 4 different epidural dosing regimes of local anaesthetic solution in a series of 3 epidural injections over a period of 12 months to determine the optimum dose of anaesthetic solution for pain relief and to determine the nature of any adverse events by measuring anxiety and depression, functionality and any side effects of the medication.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hamilton Health Sciences Corporation
• Treatments: Bupivacaine; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• 18-75 years old

• lower back pains > 6 months

• no lumbar epidural in past 6 months

• no previous back surgery

• written informed consent to participate in study

Exclusion Criteria:

• acute lower back pain

• pregnancy

• significant psychiatric disease

• local or systemic infection

• coagulopathy/anticoagulant therapy

• bleeding diathesis

• presently enrolled in another study