Epsilon Aminocaproic Acid Vs. Tranexamic Acid Vs. Placebo for Prevention of Blood Loss in Total Knee Arthroplasty
Status:
Unknown status
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
TXA and EACA have been reported to reduce blood loss in cardiac and neuro surgery, but there
is no literature available comparing the two in total knee arthroplasty (TKA). The
investigators want to determine if TXA or EACA compared with placebo are effective and safe
for blood loss prevention in TKA by comparing blood loss, transfusion rates, and total cost.