Erlotinib and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer
Status:
Completed
Trial end date:
2004-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Erlotinib may stop the growth of tumor cells by blocking the
enzymes necessary for tumor cell growth. Combining erlotinib with combination chemotherapy
may kill more tumor cells.
PURPOSE: Phase I/II trial to study the effectiveness of combining erlotinib with oxaliplatin,
leucovorin, and fluorouracil in treating patients who have metastatic colorectal cancer.