Escitalopram (Lexapro) for Depression MS or ALS

• Status: Completed
• Trial end date: 2010-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to see if escitalopram (Lexapro) improves symptoms of major depressive disorder in patients who have ALS or MS.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of South Carolina
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• Patients between 18 and 70 years of age with documented ALS or MS,

• DSM-IV episode of non-psychotic Major Depression,

• ≥14 score on the 17-item HAM-D,

• Ability to give informed consent.

Exclusion Criteria:

• History of psychotic disorders,

• Psychotic depression,

• Bipolar depression,

• Suicide risk,

• History of substance abuse in the previous 6 months,

• History of unstable medical disorders,

• Pregnancy or planning for pregnancy,

• Severity of ALS or MS that limits participating in the study protocol.