Escitalopram Treatment of Night Eating Syndrome

• Status: Completed
• Trial end date: 2011-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Night-Eating Syndrome (NES) is an eating disorder characterised by excessive eating at night, sleep disturbance and morning anorexia. This 12-week study examines the effect of escitalopram on symptoms of NES.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Duke University
• Collaborator: St. Louis University
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• Age 18-70 years

• Presence of NES

• BMI 25-50

Exclusion Criteria:

• History of schizophrenia or other psychoses

• History of bipolar disorder, anorexia nervosa, bulimia, binge eating disorder

• Current major depressive disorder

• Suicidal ideation

• Psychotropic drugs in the past month

• Drugs or herbal remedies that significantly affect body weight, current participation in a weight loss program, currently following a specialized diet (e.g., Atkins, Zone, etc)

• Lack of benefit with SSRI treatment for NES

• Serious or unstable medical illness

• Allergy or hypersensitivity to escitalopram

• Pregnant, breast-feeding, or planning pregnancy in the next six months.