Esketamine and Propofol for Children With Autism Spectrum Disorder Undergoing Colonoscopy

• Status: Completed
• Trial end date: 2023-09-20
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the dose-response relationship of esketamine in combination with propofol for children with Autism Spectrum Disorder undering colonoscopy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Second Hospital of Nanjing Medical University
• Collaborator: SIR RUN RUN hospital of Nanjing Medical University
• Treatments: Esketamine; Propofol

Criteria

Inclusion Criteria:

• （1) aged 2-12 years;

• (2) diagnosed with ASD by pediatric psychiatrists in accordance with the criteria in the Fifth Edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-V);

• (3) evaluated as American Society of Anesthesiologists (ASA) physical status I-II;

• (4) scheduled for colonic procedure.

Exclusion Criteria:

• (1) oral sedation (premedication) before intravenous catheter placement;

• (2) any contraindication to study medications;

• (3) other circumstances in which the investigator determined that a patient was not suitable for participation in the clinical trial.