Esmolol vs. Labetalol in Endoscopic Sinus Surgery

• Status: Completed
• Trial end date: 2018-03-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare esmolol and labetalol bleeding and intra-operative visibility scores in functional endoscopic sinus surgery.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Texas Medical Branch, Galveston
• Treatments: Esmolol; Labetalol

Criteria

Inclusion Criteria:

• History of CRS with or without nasal polyps

• Undergoing FESS for CRS

• American Society of Anesthesiologists (ASA) physical status 1 (healthy) or 2 (patient with mild systemic disease).

Exclusion Criteria:

• Pregnancy

• Asthma

• COPD

• Bradycardia

• Heart failure

• End stage renal disease

• Cerebrovascular accident

• Diabetes mellitus

• Preoperative use of NSAIDs, aspirin, or beta-blockers

• Body mass index (BMI) greater than 40 kg/m2.