Esomeprazole, Moxifloxacin and Amoxicilin for Rescue Therapy of Helicobacter Pylori Infection
Status:
Unknown status
Trial end date:
2008-02-01
Target enrollment:
Participant gender:
Summary
Successful H. pylori eradication therapy remains a challenge in medical practice. Despite
promising data for first-line, second-line and rescue treatment options based on clinical
trials as well as guidelines and expert recommendations, success rates can often not be
reproduced in general practice. Rescue options for patients with failed initial or
second-line therapy are definitely needed. The new fluoroquinolone moxifloxacin may represent
an effective and save treatment option (in combination with a PPI and amoxicillin) for rescue
therapy of H- pylori positive patients.However, optimal duration of therapy (7-day course vs
14-day course) has to be determined
Phase:
Phase 3
Details
Lead Sponsor:
Technische Universität Dresden
Treatments:
Amoxicillin Esomeprazole Fluoroquinolones Moxifloxacin Norgestimate, ethinyl estradiol drug combination