Estimating Apnea Phenotypes From Polysomnography: Oxygen
Status:
Completed
Trial end date:
2016-07-01
Target enrollment:
Participant gender:
Summary
This study seeks to employ advanced methods to estimate the individual factors contributing
to sleep apnea from standard recordings made during routine clinical sleep studies. This
study focuses on breathing control or "loop gain" as one of the factors contributing to sleep
apnea. Increased levels of oxygen in the air is known to make breathing more stable by
lowering "loop gain". Here, our goal is to use a new method capable of detecting a reduction
in loop gain with oxygen. The investigators also aim to test whether a high loop gain
measured at baseline/placebo predicts a greater improvement in sleep apnea with oxygen
therapy.
Phase:
N/A
Details
Lead Sponsor:
Brigham and Women's Hospital
Collaborators:
American Heart Association National Heart, Lung, and Blood Institute (NHLBI)