Overview

Estrogen Treatment (Oral vs. Patches) in Turner Syndrome

Status:
Completed
Trial end date:
2004-06-01
Target enrollment:
Participant gender:
Summary
The study attempts to evaluate if the way of administering estrogen, the principal female hormone, via patches or orally, affects the way estrogen works in girls with Turner Syndrome. These are girls who are very short and whose ovaries do not work. We will examine changes bone, protein and fat metabolism under the influence of estrogen delivered by a patch trough the skin vs estrogen taken orally. These studies are conducted while the girls are taking GH therapy.
Phase:
Phase 3
Details
Lead Sponsor:
Nemours Children's Clinic
Collaborator:
Eli Lilly and Company
Treatments:
Estradiol
Estradiol 17 beta-cypionate
Estradiol 3-benzoate
Estradiol valerate
Estrogens
Polyestradiol phosphate