During perimenopause (the time just prior to menopause), women often notice many biological,
psychological, and social changes. In particular, some women experience depressive symptoms
during perimenopause that are severe enough to warrant antidepressant medication. Whether or
not women with perimenopausal depression respond to antidepressant medication may depend on
the level of estrogen in their blood. This study will investigate whether estrogen will help
women who only partially respond to antidepressant medications, as well as examine how
different doses of estrogen may affect individuals differently.
Phase:
Phase 4
Details
Lead Sponsor:
University of California, Los Angeles
Collaborator:
National Alliance for Research on Schizophrenia and Depression