Ethanol-lock Therapy for the Prevention of Non-tunneled Catheter-related Infection in Pediatric Patients

• Status: Completed
• Trial end date: 2017-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Central venous catheter (CVC) infection is a common complication in pediatric patients, resulting in prolonged length of stay in hospital, requiring antibiotics, invasive procedures and increase morbidity and mortality. Given the repercussion of this complication, measures that minimize its should be stimulated. The purpose of this study is to evaluate the effects of intraluminal alcoholization (ethanol lock therapy) on prevention of infection of short-term central venous catheters in pediatric patients.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto Materno Infantil Prof. Fernando Figueira
• Collaborators: Bellisa Caldas Lopes; Lara Barreto Machado; Paulo Sérgio Gomes Nogueira Borges; Rodrigo Melo Gallindo; Thuanne Beatriz Silva Tenório
• Treatments: Ethanol

Criteria

Inclusion Criteria:

• Pediatric surgery patients;

• Weight: 2 Kg or more;

• Using non-tunneled double-lumen polyurethane central venous catheter;

• CVC inserted at operation room, Pediatric Intensive Care Unit (PICU) or Neonatal Intensive Care Unit (NICU);

• CVC adequately positioned (checked by radioscopy ou radiography);

• CVC implanted within a maximum of 24 hours.

Exclusion Criteria:

• Patients whose catheters had been inserted under emergency situations;

• Patients in a critical condition (those requiring continuous fluid/drug infusion through both lumens);

• Patients with a history of hypersensitivity or allergic reactions to ethanol were excluded from the study.