Overview

Etomidate/Propofol Mixture or Propofol Monotherapy Use in Patients Undergoing General Anesthesia

Status:
Unknown status
Trial end date:
2019-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study was to investigate the effects of different proportions of etomidate/propofol mixture and propofol alone intravenous anesthesia on intraoperative and postoperative physiological indicators and complications, and to find out the optimal use ratio of E/P mixture.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Guolin Wang
Treatments:
Anesthetics
Etomidate
Propofol
Criteria
Inclusion Criteria:

1. Patients undergoing elective general anesthesia surgery in 3h;

2. American Society of Anesthesiologists gradesâ… ~III;

3. Aged 18 to 65 years, Body Mass Index 18.5 ~ 29.9kg / m2;

4. Hemoglobin 100 ~ 125g / L.

5. In line with the ethics, the patients volunteered to take the test and signed the
informed consent

Exclusion Criteria:

1. Identify or suspect abuse or chronic use of narcotic sedatives and analgesics;

2. Heart, or liver, or lung, or kidney dysfunction;

3. Body mass index> 30kg / m2; or <18.5kg / m2

4. Speech, hearing or mental disorders;

5. severe diabetes, hyperkalemia ;

6. participate in other drug clinical researches in four weeks;

7. Poor compliance, can not complete clinical research by research program.

8. Any cerebrovascular accident occurred within 3 months, such as stroke, TIA, etc

9. Unstable angina and myocardial infarction occurred within 3 months;

10. Having contraindications or allergies to experimental drugs and other narcotic drugs;

11. Mental illness, hyperkalemia.