Etoricoxib vs. Diclofenac in OA (0663-805)(COMPLETED)

• Status: Completed
• Trial end date: 2002-12-20
• Target enrollment: 0
• Participant gender: All

Summary

To compare the safety and tolerability of etoricoxib and diclofenac sodium in the treatment of osteoarthritis of the knee or hip during a six week period.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Merck Sharp & Dohme Corp.
• Treatments: Diclofenac; Etoricoxib

Criteria

Inclusion Criteria:

• Patient is at least 40 years old and diagnosed with osteoarthritis of the knee or hip

• Has a history of treatment with NSAIDs with positive therapeutic benefit

• Agree to limit alcohol intake to less than 7 drinks per week and avoid unusual strenuous activity

• Females who are able to have children must have negative urine pregnancy tests

Exclusion Criteria:

• Has rheumatoid arthritis, lupus, Paget's disease affecting the study joint, or Wilson's disease

• History of acute ligament or meniscus damage to the study joint (knee or hip) within the past 2 years or arthroscopic surgery on the affected study joint with the past 6 months

• Requires joint replacement