Eval 3-Drug Therapy Diethylcarbamize, Albendazole and Ivermectin That Could Accelerate LF Elimination Outside of Africa
Status:
Completed
Trial end date:
2018-06-01
Target enrollment:
Participant gender:
Summary
This study will determine if a combination of 3 drugs used to treat the infection that cause
lymphatic filariasis (LF) due to Wuchereria bancrofti infection are more effective in killing
or sterilizing the adult worms compared to just 2 of the 3 drugs that usually given to treat
this infection. The three drugs used together are called albendazole (ALB), ivermectin (IVM)
and diethylcarbamazine (DEC). The usual treatment in Papua New Guinea (PNG) for lymphatic
filariasis are DEC and ALB. A combination of these 3 drugs has not been previously used to
treat LF.