Overview
Evaluate the Depth and Duration of Anesthesia
Status:
Completed
Completed
Trial end date:
2007-04-01
2007-04-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The purpose of the study is to determine the depth (mm) of anesthesia provided by the Synera topical patch (using sensory depth and pain depth evaluations), and to determine the duration (minutes) of anesthesia provided by the Synera topical patch (using dermal sensory testing and thermal sensory testing evaluations), compared with a matching heated placebo patch.Phase:
Phase 4Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
ZARS Pharma Inc.Collaborator:
Endo PharmaceuticalsTreatments:
Anesthetics
Lidocaine
Tetracaine
Criteria
Inclusion Criteria:- Had no known significant diseases
- Normal 12-lead electrocardiogram
- Willing to refrain from using any local topical preparations
Exclusion Criteria:
- Taken over-the-counter (OTC) or prescription analgesics in any form within 24 hours
- Known allergy or sensitivity to any component of the Synera patch, including
lidocaine, sympathomimetic amines, other local anesthetics of the amide type,
epinephrine, or other patch components
- Had an active dermatological disease of any origin that may have interfered with their
ability to participate