Evaluate the Effect and Safety of Pu Yang Wan Wu Tang and Western Medicine on Chronic Kidney Disease
Status:
Not yet recruiting
Trial end date:
2023-05-31
Target enrollment:
Participant gender:
Summary
The indication of Pu Yang Wan Wu Tang is stroke sequelae, such as half body paralysis,
aphasia and muscle weakness.
Pu Yang Wan Wu Tang is proved to have the effect of protecting nerve and blood vessel,
anti-inflammation, anti-coagulation, dilating peripheral vessel, promot-ing micro
circulation, improving hemodynamics, and activating central nerve system. Huangqi could
attenuate podocyte injury by regulating the expression and distribu-tion of nephrin and
podocin. Huangqi and Danggui are associated with fewer infiltra-tion of macrophages and
limitation of renal intrinsic cell activation, which may lead to earlier and persistent
reduction of proteinuria.
This research will use the compound Chinese medicine, Pu Yang Wan Wu Tang. Those treatments
combined Western medicine to assess the efficacy and drug safety on the CKD cases. Series of
blood and urine were collected regularly during study to prove the role of Chinese medicine
in the treatment of CKD, and to assess their drug safety.
The final goal of the plan is to establish the new indication of Pu Yang Wan Wu Tang and
enhance the interaction and cooperation between Chinese and Western medicine.