Evaluate the Effects of Formoterol and Beclomethasone Dipropionate Combination Therapy on Small Airways Function
Status:
Unknown status
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
Inuvair® is a novel fixed combination product used in the treatment of asthma and under
clinical development for the treatment of COPD. Thanks to the extrafine particle size, it is
able to target the whole bronchial tree, including the small airways and hence, is expected
to act in these airways and it may thus be beneficial in COPD in that sense. In COPD, its
action on the small airways is not directly demonstrated thus far. By way of contrast, dear
evidence is present that treatment with bronchodilators alone does not beneficially alter
small airway function. The study hypothesis states that the effects of inhaled
corticosteroids or ICS/LABA combinations on small airway is present and can be objectivated.