Overview

Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers

Status:
Completed

Trial end date:
2018-01-11

Target enrollment:

Participant gender:

Summary

This phase 1 clinical trial is to evaluate the effects of the environmental change in intestine by antibiotics on the pharmacokinetic characteristics of simvastatin in healthy male volunteers. For change of intestine environment, especially the gut microbiota, investigators will administer PO vancomycin for 7 days, tid.

Phase:

Phase 1

Details

Lead Sponsor:

Seoul National University Hospital

Treatments:

Anti-Bacterial Agents
Simvastatin
Vancomycin