Overview
Evaluating Commercial Anti-Plaque Products and Oral Rinse
Status:
Completed
Completed
Trial end date:
2007-09-01
2007-09-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Clinical research study to determine the anti-plaque efficacy of commerical dentifrices and an oral rinse.Phase:
Phase 2Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Colgate PalmoliveTreatments:
Chlorhexidine
Chlorhexidine gluconate
Fluorides
Triclosan
Criteria
Inclusion Criteria:- Male or female volunteers at least 18 years of age.
- Good general health.
- Must sign informed consent form.
- Minimum of 20 natural uncrowned teeth (excluding third molars) must be present.
- No history of allergy to personal care consumer products, or their ingredients,
relevant to any ingredient in the test products as determined by the dental/medical
professional monitoring the study.
Exclusion Criteria:
- Subjects unable or unwilling to sign the informed consent form.
- Medical condition which requires pre-medication prior to dental visits/procedures.
- Moderate or advanced periodontal disease or heavy dental tartar (calculus).
- Two or more decayed untreated dental sites at screening.
- Other disease of the hard or soft oral tissues.
- Impaired salivary function (e.g. Sjogren's syndrome or head and neck irradiation).
- Use of medications that are currently affect salivary function.
- Use of antibiotics or antimicrobial drugs within 30 days prior to study visit #1.
- Allergy to chlorhexidine.
- Pregnant or nursing women.
- Participation in any other clinical study within 1 week prior to enrollment into this
study.
- Use of tobacco products.
- Subjects who must receive dental treatment during the study dates.
- Current use of Antibiotics for pre-medication for dental treatment or for any other
purpose.
- Presence of an orthodontic appliance that interferes with plaque scoring.
- History of allergy to common dentifrice ingredients.
- Immune compromised individuals (HIV, AIDS, immuno suppressive drug therapy).