Overview
Evaluating Different Modalities for Pleural Adhesiolysis at Assuit University Hospital
Status:
Unknown status
Unknown status
Trial end date:
2020-06-30
2020-06-30
Target enrollment:
0
0
Participant gender:
All
All
Summary
interventional randomized clinical trial will be done at Assuit University Hospital ( Chest Department and Caridothoracic surgery department ),and all patients presented with complex septate pleural effusion in whom the symptoms excepted to be relieved by pleural fluid drainage will be included in our study within the two next years.Phase:
Phase 4Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Assiut UniversityTreatments:
Mesna
Streptokinase
Criteria
Inclusion Criteria:- Patients with symptomatic pleural effusion in whom the symptoms excepted to be
relieved by pleural fluid drainage.
- Presence of intrapleural adhesions as documented sonographically.
- Difficult thoracentesis.
- Failure of satisfactory pleural fluid drainage 24 hours following intercostal tube
(ICT) placement provided that the tube was properly positioned and not obstructed.
- Written consent, free and informed.
Exclusion Criteria: patients have contraindications for any of our procedures will be
excluded.
- Contraindications for streptokinase instillation i.e. (Previous allergic reaction,
bronchopleural fistula, trauma or surgery within 48 hrs, history of hemorrhagic
stroke, coagulation defects and previous streptokinase thrombolysis).
- Patients who are unfit for general anaesthesia.