Evaluating Immune Response to Seasonal FluMist in Healthy Adults
Status:
Terminated
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The Live-Attenuated Influenza Vaccine (LAIV), also known as FluMist, has been shown to be
effective in children but less effective in adults. Our hypothesis is that this relative
failure is due to adults having enough anti-flu IgA antibody in nasal secretions to
neutralize the weakened vaccine virus.
Phase:
N/A
Details
Lead Sponsor:
National Center for Occupational Health and Infection Control
Collaborators:
US Department of Veterans Affairs VA Office of Research and Development