Overview

Evaluating Newly Approved Drugs for Multidrug-resistant TB

Status:
Recruiting
Trial end date:
2023-08-01
Target enrollment:
Participant gender:
Summary
endTB Clinical Trial a Phase III, randomized, controlled, open-label, non-inferiority, multi-country trial evaluating the efficacy and safety of five new, all-oral, shortened regimens for multidrug-resistant tuberculosis (MDR-TB).
Phase:
Phase 3
Details
Lead Sponsor:
Médecins Sans Frontières France
Médecins Sans Frontières, France
Collaborators:
Epicentre
Harvard Medical School
Harvard Medical School (HMS and HSDM)
Institute of Tropical Medicine, Belgium
Interactive Research and Development
Ministry of Health, Kyrgyzstan
Ministry of Health, Lesotho
National Center for Tuberculosis and Lung Diseases, Georgia
National Center for Tuberculosis Problems, Kazakhstan
Partners in Health
Socios En Salud, Peru
Treatments:
Bedaquiline
Clofazimine
Levofloxacin
Linezolid
Moxifloxacin
Ofloxacin
Pyrazinamide