Overview

Evaluating the Effect of Candesartan vs Placebo in Prevention of Trastuzumab-associated Cardiotoxicity

Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
Evaluating the effect of the angiotensin II-receptor (AT1) blocker candesartan vs placebo in prevention of trastuzumab-associated cardiotoxicity in patients with primary breast cancer treated with trastuzumab.
Phase:
Phase 3
Details
Lead Sponsor:
The Netherlands Cancer Institute
Collaborators:
AstraZeneca
Roche Pharma AG
Treatments:
Angiotensin II
Angiotensinogen
Candesartan
Candesartan cilexetil
Trastuzumab