Evaluation of Analgesia With EMLA and Glucose Oral Solution

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

In this randomized controlled study the investigators intended to compare analgesic effects of EMLA and/or oral glucose in 60 preterm neonate during arterial function and PICC installation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Federal University of Minas Gerais
• Treatments: EMLA; Lidocaine; Prilocaine

Criteria

Inclusion Criteria:

1. Gestational age greater than or equal to 28 weeks and less than 37 weeks

2. Admission in the neonatal intensive care unit of the hospital Julia Kubtischek

3. Clinical indication of collection of blood through arterial puncture or peripherally inserted central catheter

4. Neonate in the first week of life (first to seventh day of life);

5. Informed consent have to be obtained by parents or guardians.

Exclusion Criteria:

1. Newborn with broken skin at cream application site;

2. Use of sedation or analgesia in the last 72 hours;

3. Diagnosis of necrotizing enterocolitis;

4. Anemia

5. Metabolic acidosis

6. Methaemoglobinaemia

7. Treatment with agents to induce methemoglobinemia

8. Mechanical ventilation in patients using opioids

9. Clinical diagnosis of neuromuscular dysfunction

10. Any contraindication to suction

11. Urgent procedures