Evaluation of Analgesia for Spine Fusion Elective Surgery in Children
Status:
NOT_YET_RECRUITING
Trial end date:
2029-08-31
Target enrollment:
Participant gender:
Summary
The multicenter PRECISE Analgesia (Prospective Randomized Evaluation of Analgesia for Idiopathic Scoliosis Spine Fusion Elective Surgery in Children) trials will a) implement and investigate the efficacy and safety of multidose methadone-based standardized enhanced recovery after surgery (ERAS) protocol, and b) develop personalized ERAS protocols including precision methadone and oxycodone dosing1,2 and c) personalized analgesia for the safe and effective opioid-sparing management of surgical pain after posterior spine fusion (PSF) in children.
Phase:
PHASE3
Details
Lead Sponsor:
Senthil Sadhasivam
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)