Overview

Evaluation of ETC-1907206 With Dasatinib in Advanced Haematologic Malignancies

Status:
Withdrawn
Trial end date:
2023-02-01
Target enrollment:
Participant gender:
Summary
This study evaluates the use of ETC-1907206 in combination with dasatinib in certain types of blood cancers. The first phase of the study (1A) is designed to find the highest tolerated dose of ETC-1907206, while the second phase (1B) will assess the safety and tolerability of the recommended dose of ETC-1907206. ETC-1907206 has been designed to block the activity of an enzyme of the body known as Mnk kinase, which is thought to be involved in the development of a variety of cancers.
Phase:
Phase 1
Details
Lead Sponsor:
D3 (Drug Discovery and Development), A*STAR Research Entities
EDDC (Experimental Drug Development Centre), A*STAR Research Entities
Collaborator:
Chiltern International Inc.
Treatments:
Dasatinib