Evaluation of Effects of Exercise Training and ARB in DM Patients

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aims of this clinical trial are to assess the impacts on vascular function tests and circulating biomarkers of a short-term (12-week) low-to-median intensity exercise training or ARBs treatment in patients with DM and hypertension.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Taiwan University Hospital
• Collaborator: Daiichi Sankyo Taiwan Ltd.
• Treatments: Olmesartan; Olmesartan Medoxomil

Criteria

Inclusion Criteria:

• patients with diabetes mellitus and hypertension

• age 30-70 years，systolic blood pressure 140-160 mmHg and HbA1c ≤ 8%,

• no history of ACEI or ARB use within 6 months

Exclusion Criteria:

• active cardiovascular diseases

• severe hepatic

• renal dysfunction (CRE ≥ 3 mg/dl，T-Bil ≥ 3 mg/dl)