Overview

Evaluation of Efficacy and Safety of Iloperidone in the Treatment of Bipolar I Disorder

Status:
Recruiting
Trial end date:
2023-05-01
Target enrollment:
0
Participant gender:
All
Summary
The aim of this study is to investigate the efficacy, safety, and tolerability of iloperidone compared with placebo in treating acute manic or mixed episodes associated with Bipolar I Disorder.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Vanda Pharmaceuticals
Treatments:
Iloperidone
Criteria
Inclusion Criteria:

- Male or female patients 18 to 65 years of age (inclusive)

- Diagnosed with bipolar I disorder, manic or mixed-type, per DSM-5 criteria

- Voluntary hospitalization for current manic episode

Exclusion Criteria:

- Patients with a DSM-5 diagnosis of a psychiatric disorder other than bipolar I
disorder that was the primary focus of treatment within the previous six months

- Patients who are experiencing a first manic episode or meeting criteria for rapid
cycling