Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients

• Status: Completed
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether full-mouth disinfection is effective in the initial periodontal treatment of generalized aggressive periodontitis on clinical parameters, gingival crevicular fluid interleukin-1β (IL-1β) and interleukin-17 (IL-17) and periodontal pathogen levels compared with conventional initial periodontal treatment and full-mouth initial periodontal treatment.

The investigators' hypothesis is to test whether full-mouth disinfection in the initial periodontal treatment of generalized aggressive periodontitis enhance the clinical, biochemical and microbiological parameters in comparison to conventional initial periodontal treatment and full-mouth initial periodontal treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Marmara University

Criteria

Inclusion Criteria:

• No systemic diseases that could influence the outcome of the therapy

• No smoking

• No medications affecting periodontal tissues

• No pregnancy or lactation

• Presence of at least 15 teeth

Exclusion Criteria:

• Received antibiotic treatment in the previous 3 months

• Smokers

• Pregnancy and lactation

• Received periodontal treatment in the previous 6 months

• Presence of less than 15 teeth

• Presence of systemic diseases