Evaluation of Efficacy of Levamisole and Formoterol+Budesonide in Treatment of COVID-19
Status:
Recruiting
Trial end date:
2020-05-20
Target enrollment:
Participant gender:
Summary
New Corona virus (COVID-19) has made a horrible situation for all of the countries. This
disease is not only a health problem but also economy, culture and the whole entity of the
countries is under attack by the virus. This disease seems to affect the body in two
different pathology pathways. From one side virus can decrease activity of immune system in
the blood stream and whole body and from other side it can attack the respiratory cells.
Tissue biopsy shows that immune cells penetrate into the Lung tissue and we have accumulation
and over activity of Immune cells in the lung. This inflammation in respiratory tract
probably is the major cause of Cytokine storm and release of TNF-α and IL-6 into the blood.
It seems that by three strategy disease can be treated. 1- By using systemic immune
simulators. 2- By using topical anti-inflammatory drug in the respiratory system (Steroids or
NSAIDs) 3- By inhibition of replication of the virus in the attacked cells.