Overview

Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in Children

Status:
Completed
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
This is an open label uncontrolled study to determine the efficacy of fosmidomycin and clindamycin when co-administered orally over three days in the treatment of acute uncomplicated Plasmodium falciparum malaria in children. The primary study endpoints will be the cure rate on Day 28 (PCR corrected). The secondary endpoints will be the cure rate on Day 7 and the parasite and fever clearance times.
Phase:
Phase 2
Details
Lead Sponsor:
Jomaa Pharma GmbH
Collaborators:
Fundacio Clinic
Fundacio Clinic Barcelona
Hospital Clinic of Barcelona
Treatments:
Clindamycin
Clindamycin palmitate
Clindamycin phosphate
Fosfomycin
Fosmidomycin