Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Patients With Meniere's Disease

• Status: Terminated
• Trial end date: 2020-09-01
• Target enrollment: 0
• Participant gender: All

Summary

• This prospective study aims to better characterize inner ear's perilymphatic structures with Magnetic Resonance Imaging using contrast media and delayed injection in patient's with Meniere's disease.

• MR Perfusion Imaging will be assess in both cochlea as well

• Primary auditory brain pathways will be evaluated through MR diffusion imaging

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Grenoble
• Collaborator: Guerbet

Criteria

Inclusion Criteria:

• Major subjects of over 40 years (mean age of Meniere's disease 40 to 50 years)

• Informed consent signed

• Medical examination performed prior to participation in research

• Patients with clinical criteria of Meniere's disease according to the classification of the American Association of Otology (ie the combination of a sensorineural hearing loss at low frequencies, recurrent vertigo and tinnitus and / or clogged ear sensation)

• Recipient of a French social security scheme

Exclusion Criteria:

• Patients minors

• Patients on a legal protection regime type guardianship

• Respiratory pathologies, cardiovascular, renal, diabetes

• Claustrophobia

• Contraindications to exposure to a magnetic field

• Contraindications to injecting Dotarem ®