Evaluation of Ketamine and Multi-modal Analgesics

• Status: Withdrawn
• Trial end date: 2018-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research study is to see if pain can be better controlled with fewer side effects. The new drug regimen will study several different medicines that have different ways of treating pain.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Florida
• Treatments: Acetaminophen; Analgesics; Gabapentin; Ketamine; Lidocaine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) status 1-4

• Undergoing planned surgery for cardiac problems

• 18 years of age and not older than 85 years of age

Exclusion Criteria:

• Severe liver disease (alanine aminotransferase (ALT) , aspartate aminotransferase (AST), or bilirubin > 2.5 times Upper Limit of Normal)

• Pregnancy or currently breastfeeding

• History of schizophrenia or other hallucinatory psychiatric disorder

• History of chronic or pre-existing pain disorder

• History of heart block

• Severe renal impairment Creatinine Clearance (CrCl)<30 milliliter(mL)/min