Evaluation of Laser and Tranexamic Acid in Treatment of Melasma

• Status: Not yet recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Melasma Is an acquired, chronic, recurrent, symmetrical hypermelanosis, which is characterized by brown patches of variable darkness on sun exposed areas of the body. It is more common in women. It is common psychologically and emotionally distressing cosmetic problem in affected patients .

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• - Gender: Only female patients.

• Age: 18-50 years old.

• Type of melasma: Bilateral symmetrical facial melasma of all types.

• Fitzpatrick skin phototypes: Types III, IV and V.

Exclusion Criteria:

• - Pregnancy and lactation.

• Patients taking oral contraceptive pills, hormonal replacement therapy or isotretinoin at the time of the study or during the past 6 months. Concomitant use of anticoagulants, bleeding disorders.

• Scarring and keloid tendency, active skin infections, active HSV, and those with facial cancer.

• History of photosensitivity or photosensitizing medications such as sulfonamides and tetracycline.

• Previous history of post inflammatory hyperpigmentation.