Overview Evaluation of Losartan and Perindopril in Blacks Type 2 Diabetics Patients Status: Completed Trial end date: 2018-04-30 Target enrollment: Participant gender: Summary The aim of this study is to compare the short-term effects of ACEi and angiotensin II receptor blockers on cardiac and renal protection in black type 2 diabetics patients CARE-PLP is a double-arm, double-blind, randomized and parallel clinical trial conducted at the National Obesity Center in the Yaoundé Central Hospital. A population of Type 2 diabetes patients, with hypertension and / or microalbuminuria and who are not taking ACEi or angiotensin receptors blockers, is randomize into two groups. Depending on the group, 10 mg Perindopril or 100 mg Losartan is add to the usual treatment for each patient. The patients are followed-up for a period of 08 weeks. The primary outcome is the variation of exercise induced urinary albumin excretion after 08 weeks of intervention. Phase: Phase 4 Details Lead Sponsor: Yaounde Central HospitalTreatments: LosartanPerindopril