Evaluation of Metronidazole Hydrogel 25% in Stage II and III Periodontitis

• Status: Completed
• Trial end date: 2021-07-07
• Target enrollment: 0
• Participant gender: All

Summary

A randomized clinical trial will be performed single-blind to evaluate the effectiveness of sublingual metronidazole hydrogel 25 % in periodontitis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of L'Aquila
• Treatments: Metronidazole

Criteria

Inclusion Criteria:

• 10% of sites with survey depth 5 mm

• Comparable pockets in 4 mouth quadrants

• Health at systemic level

Exclusion Criteria:

• Changes in oral mucosa

• Depth at the poll 5 mm

• Presence of removable prostheses or orthodontic equipment

• Allergies to even a single component of a product in testing• Antibiotic-based treatments during the 6 months preceding the start of testing

• History of previous periodontal treatments in the 12 months preceding the start of the study