Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity

• Status: Not yet recruiting
• Trial end date: 2025-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The major objective of this project is to examine whether daily consumption of milk polar lipids (MPLs) influences cardiometabolic risk factors.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Connecticut
• Collaborator: Dairy Management Inc.

Criteria

Inclusion Criteria:

• LDL-C ≥ 130 mg/dL

• Waist circumference ≥ 88 cm for women, ≥ 102 cm for men

• Aged 40 to 70 years

Exclusion Criteria:

• Renal disease

• Liver disease

• Diabetes

• Heart disease

• Stroke

• Cancer

• Eating disorders

• Thyroid disease

• Gut-associated pathologies

• Autoimmune diseases

• Chronic inflammatory diseases

• Scleroderma

• Gallbladder disease

• Blood clotting disorders

• Intravenous drug use

• Self-reported pre-menopausal status

• Fasting plasma/serum triglycerides >500 mg/dL

• Fasting plasma/serum glucose >126 mg/d

• Weight changes >10% over last 4 weeks

• Oral antibiotics use up to 1 month prior to and during study

• Allergy or intolerance to milk products

• Taking lipid-lowering medications (e.g., statins, fibrates)

• Taking anti-inflammatory medications (e.g., corticosteroids)

• Taking medications which primarily affect blood clotting (e.g., warfarin).