Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology

• Status: Unknown status
• Trial end date: 2010-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this pilot study is to estimate a procedure where the biological samples routinely obtained at the site of suspected infection could be guided by the early realization of a TEP with FDG coupled to scanner X, in patients hospitalized in ICU for severe sepsis of unspecified etiology.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Central Hospital, Nancy, France

Criteria

Inclusion Criteria:

• Patient hospitalized with severe sepsis

• Absence of infected site clearly identified after 48 hours of a conventional diagnosis assessment or suspicion of one or more additional sites

• Indication of scanner X with injection

• Informed consent obtained

Exclusion Criteria:

• Age over 80

• Immunocompromised status

• Surgical intervention within the previous month

• Hemodynamic instability (defined by the use of more than 0.5µg/kg/min vasopressors)

• Severe hypoxia (defined by a PaO2/FiO2 ratio lower than 150)

• Pregnancy

• Patient already included in another protocol

• Anaphylaxis to Flucis