Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Patients undergoing primary total knee replacement will receive either motor sparing knee block to be performed by anesthesia or periarticular local anesthetic infiltration at the end of surgery by surgeons to assess pain relief as well as capacity to ambulate early. The motor sparing knee block will be performed prior to surgery using ultrasonography and the effect of adding dexmedetomidine, an alpha 2 agonist to the injectate with regards to prolonging the duration of analgesia will be assessed.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lawson Health Research Institute
• Treatments: Dexmedetomidine; Epinephrine; Epinephryl borate; Ketorolac; Ketorolac Tromethamine; Morphine; Racepinephrine; Ropivacaine

Criteria

Inclusion Criteria:

1. Male and females of 18-85 years of age, scheduled to undergo elective primary total knee arthroplasty.

2. ASA Class I, II, III

3. Good contralateral leg strength

Exclusion Criteria:

1. ASA physical status 4 or above

2. Patients who will need hospitalization due to reason other than the planned surgery.

3. Psychiatric illnesses.

4. Revision knee surgery

5. Narcotic dependency

6. Extraneous sources of chronic pain

7. Inability to provide informed consent.

8. Allergy to any of the drugs used in the study.

9. Contraindications to blocks and multimodal analgesia

10. Wheel chair bound