Evaluation of Mucoadhesive Tacrolimus Patch on Caspase-3 Inducing Apoptosis in Oral Lichen Planus
Status:
Completed
Trial end date:
2021-10-20
Target enrollment:
Participant gender:
Summary
tacrolimus has been widely used as an immunosuppressant. the objective of this study was to
evaluate the clinical efficacy of tacrolimus 0.1 % in muco adhesive patch compared to
tacrolimus or corticosteroids in paste forms for symptomatic oral lichen planus, and to
investigate the effect of topical tacrolimus or corticosteroids on the expression of
caspase-3 in oral lichen planus as an early marker of apoptosis using immunohistochemically
analysis