Evaluation of Neuroinflammation in Children With Infantile Spasms

• Status: Completed
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to investigate the presence of neuroinflammation in children with infantile spasms using 11C-PK11195 positron emission tomography (PK PET) scan, and its response to ACTH treatment by repeating the PK PET scan after treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Wayne State University
• Treatments: PK 11195

Criteria

Inclusion Criteria:

• A clinical diagnosis of 'cryptogenic IS'

• Normal MRI

• No other neurological disorder

Exclusion Criteria:

• Abnormal MRI

• No anti-inflammatory medication 48 hrs prior to PK PET scans

• Parent/guardian unable to give written consent