Evaluation of Omeprazole Effect on Glaucoma

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Omeprazole is a safe drug listed in OTC drug due to its safety. It acts by irreversible inhibition of K/H ATP ase pump and also Na/K ATP ase, Na/H ATP ase.Considering these actions the effect of omeprazole on decreasing intra ocular pressure is an issue of debate.In this Randomized Clinical Trial conducted in labafinejad hospital, patients with glaucoma who need to take omeprazole due to GI problem are evaluated in two groups including placebo and drug users. The effect will be finally assessed.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shahid Beheshti University of Medical Sciences
• Collaborator: Ophthalmic Research Center
• Treatments: Omeprazole

Criteria

Inclusion Criteria:

• patients with glaucoma

• 18 to 70 years

• POAG patients, Pseudoexfoliation

• no history of other systemic disease

• no history of intraocular intervention

• no history of H2 blocker or PPI consumption during the past month consuming 2 or less topical anti-glaucoma medication

• no present immune deficiency

• no addiction habit

Exclusion Criteria: