Evaluation of Oral Hygiene Products in an In Situ Caries Model
Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
The study will evaluate and compare the potential anti-caries efficacy of a test regimen:
placebo (fluoride free) toothpaste (twice daily use) plus fluoride mouthwash (once daily
use), in comparison with brushing with a placebo toothpaste alone (twice daily use), to
remineralize previously demineralized enamel specimens, as measured by Surface MicroHardness
Recovery (%SMHR).
This will be a single center, randomized, laboratory analyst blinded, placebo, four
treatment, cross-over study in healthy participants. Participants will be assessed at
baseline and at the beginning and end of each treatment visit to monitor clinical efficacy
and safety.