Evaluation of Oral Morphine Gel in Oral Mucositis Induced by Chemotherapy in Children and Young Adults
Status:
Unknown status
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Chemotherapy kills tumor cells but can also damage healthy cells and cause significant
digestive disorders such as ulcers of the mouth, called mucositis. Mucositis are transient
but their intensity may require special measures. Mucositis are painful and morphine gel or
intravenous morphine is used to relieve pain.
However, the pain of oral mucositis induced by chemotherapy is not completely relieved by
morphine administered intravenously.
As part of the study, the investigators want to evaluate an oral gel containing a small
amount of morphine so that it acts directly on the mucositis. The investigators believe that
the direct action of morphine on mucositis may be more effective on pain.