Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse

• Status: Completed
• Trial end date: 2019-03-04
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to investigate the impact of a bromelain pre-rinse adjunct on oral plaque removal in orthodontic subjects. The study's null hypothesis states that there is no statistically significant difference in visual plaque scores among orthodontic subjects with or without proteolytic enzyme rinse aid.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Indiana University
• Collaborators: Delta Dental Foundation; Water Pik, Inc.

Criteria

Inclusion Criteria:

• male or female

• 10 to 25 years of age

• willing to consent to participation

• able to follow study instructions

• in active orthodontic treatment with fixed orthodontic appliances

Exclusion Criteria:

• unwilling/unable to follow study instructions

• documented/suspected pineapple allergy

• proteolytic enzyme allergy

• food dye allergy

• smoker