Evaluation of Penetration of Ceftobiprole Into Soft Tissue Determined by Microdialysis in Healthy Volunteers
Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to measure the penetration of ceftobiprole into
subcutaneous (s.c.) adipose tissue and skeletal muscle and to determine the concentration
over time of ceftobiprole in these tissues and in plasma after administration of a single
intravenous (i.v.) infusion (directly into the vein) of ceftobiprole 500 mg administered over
2 hours. The secondary objective was to further assess the safety and tolerability of
ceftobiprole after a single i.v. infusion.